Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion.
Identifieur interne : 000161 ( Main/Exploration ); précédent : 000160; suivant : 000162Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion.
Auteurs : H C Diener [Allemagne] ; R. Bernstein [États-Unis] ; K. Butcher [Canada] ; B. Campbell [Australie] ; G. Cloud [Royaume-Uni] ; A. Davalos [Espagne] ; S. Davis [Australie] ; J M Ferro [Portugal] ; M. Grond [Allemagne] ; D. Krieger [Suisse] ; G. Ntaios [Grèce] ; A. Slowik [Pologne] ; E. Touzé [France]Source :
- International journal of stroke : official journal of the International Stroke Society [ 1747-4949 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- usage thérapeutique : Antithrombiniques, Dabigatran.
- Accident vasculaire cérébral, Encéphalopathie ischémique, Humains, Thrombectomie, Traitement thrombolytique.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antithrombins, Dabigatran.
- prevention & control : Brain Ischemia, Stroke.
- therapy : Brain Ischemia, Stroke.
- Humans, Thrombectomy, Thrombolytic Therapy.
Abstract
Systemic thrombolysis with rt-PA is contraindicated in patients with acute ischemic stroke anticoagulated with dabigatran. This expert opinion provides guidance on the use of the specific reversal agent idarucizumab followed by rt-PA and/or thrombectomy in patients with ischemic stroke pre-treated with dabigatran. The use of idarucizumab followed by rt-PA is covered by the label of both drugs.
DOI: 10.1177/1747493016669849
PubMed: 27694315
Affiliations:
- Allemagne, Australie, Canada, Espagne, France, Grèce, Pologne, Portugal, Royaume-Uni, Suisse, États-Unis
- Angleterre, Basse-Normandie, Canton de Zurich, Catalogne, Grand Londres, Illinois, Région Normandie, Victoria (État)
- Barcelone, Caen, Londres, Melbourne, Zurich
- Université autonome de Barcelone, Université de Melbourne, Université de Zurich
Links toward previous steps (curation, corpus...)
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- to stream PubMed, to step Checkpoint: 001352
- to stream Ncbi, to step Merge: 003C44
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Le document en format XML
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Bernstein</name><affiliation wicri:level="2"><nlm:affiliation>2 Northwestern Stroke Program, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>2 Northwestern Stroke Program, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Butcher, K" sort="Butcher, K" uniqKey="Butcher K" first="K" last="Butcher">K. Butcher</name><affiliation wicri:level="1"><nlm:affiliation>4 Division of Neurology, University of Alberta, Edmonton, AB, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>4 Division of Neurology, University of Alberta, Edmonton, AB</wicri:regionArea><wicri:noRegion>AB</wicri:noRegion></affiliation></author><author><name sortKey="Campbell, B" sort="Campbell, B" uniqKey="Campbell B" first="B" last="Campbell">B. Campbell</name><affiliation wicri:level="4"><nlm:affiliation>5 Department of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>5 Department of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Cloud, G" sort="Cloud, G" uniqKey="Cloud G" first="G" last="Cloud">G. Cloud</name><affiliation wicri:level="3"><nlm:affiliation>6 The Department of Neurology, Atkinson Morley's Wing, St George's University Hospitals NHS Foundation Trust, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>6 The Department of Neurology, Atkinson Morley's Wing, St George's University Hospitals NHS Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Davalos, A" sort="Davalos, A" uniqKey="Davalos A" first="A" last="Davalos">A. Davalos</name><affiliation wicri:level="4"><nlm:affiliation>7 Department of Neurosciences, Hospital Germans Trias I Pujol, Universidad Autònoma de Barcelona, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>7 Department of Neurosciences, Hospital Germans Trias I Pujol, Universidad Autònoma de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université autonome de Barcelone</orgName></affiliation></author><author><name sortKey="Davis, S" sort="Davis, S" uniqKey="Davis S" first="S" last="Davis">S. Davis</name><affiliation wicri:level="4"><nlm:affiliation>8 Department of Translational Neuroscience, University of Melbourne, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>8 Department of Translational Neuroscience, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Ferro, J M" sort="Ferro, J M" uniqKey="Ferro J" first="J M" last="Ferro">J M Ferro</name><affiliation wicri:level="1"><nlm:affiliation>9 Department of Neurosciences and Mental Health, Hospital Santa Maria - CHLN, University of Lisbon, Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>9 Department of Neurosciences and Mental Health, Hospital Santa Maria - CHLN, University of Lisbon, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Grond, M" sort="Grond, M" uniqKey="Grond M" first="M" last="Grond">M. Grond</name><affiliation wicri:level="1"><nlm:affiliation>10 Department of Neurology, Kreisklinikum Siegen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>10 Department of Neurology, Kreisklinikum Siegen</wicri:regionArea><wicri:noRegion>Kreisklinikum Siegen</wicri:noRegion><wicri:noRegion>Kreisklinikum Siegen</wicri:noRegion><wicri:noRegion>Kreisklinikum Siegen</wicri:noRegion></affiliation></author><author><name sortKey="Krieger, D" sort="Krieger, D" uniqKey="Krieger D" first="D" last="Krieger">D. Krieger</name><affiliation wicri:level="4"><nlm:affiliation>11 Comprehensive Stroke Center, University of Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>11 Comprehensive Stroke Center, University of Zurich, Zurich</wicri:regionArea><orgName type="university">Université de Zurich</orgName><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Ntaios, G" sort="Ntaios, G" uniqKey="Ntaios G" first="G" last="Ntaios">G. Ntaios</name><affiliation wicri:level="1"><nlm:affiliation>13 Department of Medicine, University of Thessaly, Larissa, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>13 Department of Medicine, University of Thessaly, Larissa</wicri:regionArea><wicri:noRegion>Larissa</wicri:noRegion></affiliation></author><author><name sortKey="Slowik, A" sort="Slowik, A" uniqKey="Slowik A" first="A" last="Slowik">A. Slowik</name><affiliation wicri:level="1"><nlm:affiliation>14 Department of Neurology, Medical College, Jagiellonian University, Krakow, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>14 Department of Neurology, Medical College, Jagiellonian University, Krakow</wicri:regionArea><wicri:noRegion>Krakow</wicri:noRegion></affiliation></author><author><name sortKey="Touze, E" sort="Touze, E" uniqKey="Touze E" first="E" last="Touzé">E. Touzé</name><affiliation wicri:level="3"><nlm:affiliation>15 Normandie University, UNICAEN, Inserm U919, Department of Neurology, Caen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>15 Normandie University, UNICAEN, Inserm U919, Department of Neurology, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author></analytic><series><title level="j">International journal of stroke : official journal of the International Stroke Society</title><idno type="eISSN">1747-4949</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antithrombins (therapeutic use)</term><term>Brain Ischemia (prevention & control)</term><term>Brain Ischemia (therapy)</term><term>Dabigatran (therapeutic use)</term><term>Humans</term><term>Stroke (prevention & control)</term><term>Stroke (therapy)</term><term>Thrombectomy</term><term>Thrombolytic Therapy</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Accident vasculaire cérébral ()</term><term>Antithrombiniques (usage thérapeutique)</term><term>Dabigatran (usage thérapeutique)</term><term>Encéphalopathie ischémique ()</term><term>Humains</term><term>Thrombectomie</term><term>Traitement thrombolytique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antithrombins</term><term>Dabigatran</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Brain Ischemia</term><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Brain Ischemia</term><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antithrombiniques</term><term>Dabigatran</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Thrombectomy</term><term>Thrombolytic Therapy</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Accident vasculaire cérébral</term><term>Encéphalopathie ischémique</term><term>Humains</term><term>Thrombectomie</term><term>Traitement thrombolytique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Systemic thrombolysis with rt-PA is contraindicated in patients with acute ischemic stroke anticoagulated with dabigatran. This expert opinion provides guidance on the use of the specific reversal agent idarucizumab followed by rt-PA and/or thrombectomy in patients with ischemic stroke pre-treated with dabigatran. The use of idarucizumab followed by rt-PA is covered by the label of both drugs.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Canada</li><li>Espagne</li><li>France</li><li>Grèce</li><li>Pologne</li><li>Portugal</li><li>Royaume-Uni</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Basse-Normandie</li><li>Canton de Zurich</li><li>Catalogne</li><li>Grand Londres</li><li>Illinois</li><li>Région Normandie</li><li>Victoria (État)</li></region><settlement><li>Barcelone</li><li>Caen</li><li>Londres</li><li>Melbourne</li><li>Zurich</li></settlement><orgName><li>Université autonome de Barcelone</li><li>Université de Melbourne</li><li>Université de Zurich</li></orgName></list><tree><country name="Allemagne"><noRegion><name sortKey="Diener, H C" sort="Diener, H C" uniqKey="Diener H" first="H C" last="Diener">H C Diener</name></noRegion><name sortKey="Grond, M" sort="Grond, M" uniqKey="Grond M" first="M" last="Grond">M. Grond</name></country><country name="États-Unis"><region name="Illinois"><name sortKey="Bernstein, R" sort="Bernstein, R" uniqKey="Bernstein R" first="R" last="Bernstein">R. Bernstein</name></region></country><country name="Canada"><noRegion><name sortKey="Butcher, K" sort="Butcher, K" uniqKey="Butcher K" first="K" last="Butcher">K. Butcher</name></noRegion></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Campbell, B" sort="Campbell, B" uniqKey="Campbell B" first="B" last="Campbell">B. Campbell</name></region><name sortKey="Davis, S" sort="Davis, S" uniqKey="Davis S" first="S" last="Davis">S. Davis</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Cloud, G" sort="Cloud, G" uniqKey="Cloud G" first="G" last="Cloud">G. Cloud</name></region></country><country name="Espagne"><region name="Catalogne"><name sortKey="Davalos, A" sort="Davalos, A" uniqKey="Davalos A" first="A" last="Davalos">A. Davalos</name></region></country><country name="Portugal"><noRegion><name sortKey="Ferro, J M" sort="Ferro, J M" uniqKey="Ferro J" first="J M" last="Ferro">J M Ferro</name></noRegion></country><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Krieger, D" sort="Krieger, D" uniqKey="Krieger D" first="D" last="Krieger">D. Krieger</name></region></country><country name="Grèce"><noRegion><name sortKey="Ntaios, G" sort="Ntaios, G" uniqKey="Ntaios G" first="G" last="Ntaios">G. Ntaios</name></noRegion></country><country name="Pologne"><noRegion><name sortKey="Slowik, A" sort="Slowik, A" uniqKey="Slowik A" first="A" last="Slowik">A. Slowik</name></noRegion></country><country name="France"><region name="Région Normandie"><name sortKey="Touze, E" sort="Touze, E" uniqKey="Touze E" first="E" last="Touzé">E. Touzé</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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